How much does Skyrizi cost?

How we calculated these numbers

1. Dosing. The FDA label for plaque psoriasis: 150 mg at week 0, week 4, and every 12 weeks after. That’s 5 doses in year one (weeks 0, 4, 16, 28, 40), then 4 or 5 doses in any later 12-month stretch. One carton holds one dose.¹²
2. Price. Skyrizi’s list price is $23,838.42 per dose (AbbVie, as of January 6, 2026). Insurance and program costs are figured from that price, one dose at a time.¹
3. Commercial insurance. We run every dose through your plan in order: the deductible first, then your copay or coinsurance, until you reach your out-of-pocket maximum. The table’s low end uses the average specialty-tier copay ($111) with no deductible; the high end uses the average coinsurance (27%) after the average single deductible ($1,886),⁶ capped at the 2026 federal out-of-pocket limit ($10,600).⁹ Averages are from the KFF 2025 Employer Health Benefits Survey; the calculator lets you enter your own plan.
4. Skyrizi Complete. The card pays your plan’s share of each dose down to $0, up to $14,000 per calendar year (AbbVie’s published maximum). We assume your plan counts those payments toward your deductible and out-of-pocket maximum; plans with accumulator or maximizer programs aren’t eligible.²
5. Medicare Part D. The 2026 standard benefit: a deductible of up to $615, then 25% coinsurance, with total out-of-pocket costs capped at $2,100.⁷ With Extra Help, each brand-name fill costs $12.65 or less.¹⁰
6. Medicaid. $0 (many states) up to $8 per prescription, the federal limit for a non-preferred drug for enrollees with income at or below 150% of the poverty level, times the number of doses.⁸ Above that income, states can charge a percentage of the drug’s cost, and all Medicaid cost sharing is capped at 5% of household income.
7. myAbbVie Assist. $0 for people the program approves.³
8. Out of pocket. Low end: AbbVie’s list price (wholesale acquisition cost), $23,838.42 per dose as of January 6, 2026. High end: the national average retail pharmacy price without insurance or discounts, $29,677.13 per 150 mg pen (GoodRx, September 2026)⁵. We multiply each by the number of doses: 5 in year one, then 4 or 5 a year.¹
9. Care costs in the calculator. Honeydew membership starts at $25/month with an annual plan, so we use $25 × 12.⁴ On a commercial plan, the With Honeydew estimate includes the Skyrizi Complete Savings Card, which we help you enroll in; the Traditional estimate uses your plan alone. Traditional care uses four in-office dermatology visits a year (a first visit and quarterly follow-ups), priced the way your coverage pays for them: the average specialist copay ($45, KFF 2025);⁶ Medicare Part B’s 20% of the 2026 fee schedule ($177.36 new visit, $135.61 follow-up, national), with or without the $283 Part B deductible;^13,14 up to $4 on Medicaid (the limit at the lowest income level);⁸ or $100–$300 per visit without insurance (Honeydew’s figure for in-office dermatology).¹⁵ On commercial plans, visit copays count toward the same out-of-pocket maximum as the medication, so they stop once you reach it.